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更新時(shí)間：2022-10-29 15:59:53瀏覽次數(shù)：190次
聯(lián)系我時(shí)，請告知來自 環(huán)保在線Electric Von Frey電子機(jī)械
電子測痛儀也叫做電子觸覺測試儀，用于對大鼠、小鼠足部進(jìn)行輕觸，來測量老鼠的機(jī)械痛閾值或觸覺閾值。
老鼠感覺到爪子被刺激時(shí)，會做出縮足反應(yīng)。電子觸覺測試儀使用測試探針對老鼠足底進(jìn)行觸覺刺激，力度由小到大逐漸增加力度，通過判斷老鼠的縮足反應(yīng)，來采集和分析老鼠的觸覺閾值。
纖毛機(jī)械刺激絲套裝。但是纖毛機(jī)械刺激絲的方法非常耗時(shí)耗力，一個(gè)測試實(shí)驗(yàn)需要使用多個(gè)不同纖維絲進(jìn)行多次和反復(fù)足底刺激。
Von Frey電子測痛儀的主要規(guī)格
· 提供三種測試量程90g、800g和1000g；
· 支持多個(gè)用戶用一個(gè)個(gè)體支持做多個(gè)研究；
· 有剛性探針和軟絲可供選擇；
· 剛性測試探針可用率評估機(jī)械痛（閾值）
· 軟性探針可用來測試感官閾值；
主要型號和配置
· 2390型測試量程90g，精度0.01g
· 2091型測試量程800g，精度0.1g
· 23931型測試量程1000g，精度0.1g
· 2392型包含90g測試量程的2390測試儀和1套Supertips測試軟絲
· 2393型包含800g測試量程的2091型測試儀和1套Supertips測試軟絲
· 115VFHS15件套Supertips測試軟絲
· 110RT標(biāo)準(zhǔn)測試探頭
電子觸覺測試儀可用來替代傳統(tǒng)的 Semmes-Weinstein（Von Frey Hairs）纖毛機(jī)械刺激針，可直接測得動(dòng)物的機(jī)械痛閾和觸覺閾測量，不需要進(jìn)行反復(fù)的測試和繁雜的計(jì)算。設(shè)備輕巧易用，測量精確。
電子觸覺測試儀相比傳統(tǒng)方法的優(yōu)勢特點(diǎn)
· 電子觸覺測試儀，一個(gè)測試實(shí)驗(yàn)只需要進(jìn)行一次足底刺激即可得到準(zhǔn)確的結(jié)果；
· 數(shù)據(jù)可直接用于統(tǒng)計(jì)分析，能夠節(jié)省很多的精力和時(shí)間；
· 測量精度高，測試力度能夠讀取到1000g以內(nèi)的具體數(shù)值，精度可達(dá)0.1g；
· 不需要進(jìn)行繁雜的統(tǒng)計(jì)和計(jì)算；
· 使用一個(gè)標(biāo)準(zhǔn)直徑的剛性探針進(jìn)行測試，能夠避免不同力度纖維絲具有不同的直徑而產(chǎn)生的觸覺誤差；
· 能夠避免因?yàn)榉磸?fù)多次的測試對動(dòng)物耐受力的影響，減小測試誤差；
|
人體觸覺測試 |
小鼠足底觸覺測試 |
Electric Von Frey電子測痛儀的主要參數(shù)
· 配備通用的接頭，測試手柄可插入三種不同規(guī)格的探針
· 標(biāo)配LCD顯示屏(Floating or last max. & minimum)
· 剛性探頭能達(dá)800Gr；
· 可選配Supertips軟性測試絲，規(guī)格15-65Gr；
· 探針兼容MRI環(huán)境；
· 電子微處理器兼容0.1Gr插入式探針；
· 測試絲耐潮，耐溫；
· 可選配模擬輸出線；
· 可根據(jù)實(shí)際需要定制探針；
· 具有測量、存儲和顯示功能，免除了傳統(tǒng)纖維絲的繁雜計(jì)算；
· 可以預(yù)設(shè)和選擇大限額力度，精度1g，當(dāng)達(dá)到預(yù)設(shè)值時(shí)，警示燈會亮；
· 實(shí)驗(yàn)簡便安裝在測試手柄上的探針對準(zhǔn)實(shí)驗(yàn)對象，均勻施力，儀器能快速的顯示結(jié)果并記錄測試值；
· 數(shù)據(jù)可實(shí)時(shí)記錄；
· 所有型號的電子測痛儀已在出廠前校準(zhǔn)完畢，不再需要額外的校準(zhǔn)設(shè)備；
大鼠小鼠足底觸覺測試籠
大小鼠足底測試平臺，也叫做老鼠足底觸覺測試鑿孔臺，主要用于配合Von Frey電子測痛儀，對大鼠、小鼠進(jìn)行足底觸覺測試。
足底測試平臺由三部分組成鑿孔臺、測試鼠籠和45°鏡面（額外選配）
Supertips測試軟絲
Supertips采用技術(shù)，有15根測試軟絲組成。所有15根測試絲的直徑的都在0.8mm，受測的接觸面積具有高度的均一性。配合電子測痛儀使用，用于觸覺閾值（Sensory Threshold）的測量。
Supertips測試絲采用特殊PP材質(zhì)，受溫度、濕度影響小，也有利于減少實(shí)驗(yàn)誤差。
測試結(jié)果準(zhǔn)確性高，可以直接用于評估痛閾，而不需復(fù)雜的計(jì)算。
部分參考文獻(xiàn)
[HTML] An electronic pressure-meter nociception paw test for mice
TM Cunha, WA Verri Jr, GG Vivancos… - Brazilian Journal of …, 2004 - SciELO Brasil
... an inflammatory process and sensitized the paws of mice with different doses of carrageenin
ａnd prostaglandin E 2 (PGE 2 ... consisted of a hand-held force transducer fitted with a 0.5 mm
2 polypropylene tip (electronic von Frey anesthesiometer, IITC Inc., Life ...
[HTML] Pharmacological characterisation of a rat model of incisional pain
GT Whiteside, J Harrison, J Boulet… - British journal of …, 2004 - Wiley Online Library
... Pharma, Neuropharmacology, 6 Cedar Brook Drive, Cranbury, NJ 08512, USA E-mail: garth ... Issue
published online: 2 FEB 2009; Article first published online: 2 FEB 2009; ... previously described
in this model: tactile allodynia using an automated electronic von Frey (IITC, CA, USA ...
Pharmacological characterization of the chronic constriction injury model of neuropathic pain
J De Vry, E Kuhl, P Franken-Kunkel, G Eckel - European journal of …, 2004 - Elsevier
... 4 December 2003 Revised 1 March 2004 Accepted 25 March 2004 Available online 10 May
2004. Abstract. ... Mechanical allodynia was measured by means of a pressure transducer (electronic
von Frey Anaesthesiometer, IITC-Life Science Instruments, Woodlａnd Hills, CA). ...
Selective activation of cannabinoid CB2 receptors suppresses neuropathic nociception induced by treatment with the chemotherapeutic agent paclitaxel in rats
EJ Rahn, AM Zvonok, GA Thakur, AD Khanolkar… - … of Pharmacology and …, 2008 - ASPET
... E-mail: ahohmann{at}uga.edu. Next Section. Abstract. ... Mechanical withdrawal thresholds were
assessed using a digital electronic von Frey anesthesiometer (IITC model Alemo 2290-4; IITC
Life Sciences Inc., Woodlａnd Hills, CA) equipped with a rigid tip. ...
Pharmacological and pharmacokinetic characterization of the cannabinoid receptor 2 agonist, GW405833, utilizing rodent models of acute and chronic pain, anxiety, …
KJ Valenzano, L Tafesse, G Lee, JE Harrison… - …, 2005 - Elsevier
... 2004 Revised 26 November 2004 Accepted 10 December 2004 Available online 19 February ...
The marble-burying behavior model of anxiety (Njung'e ａnd Handley, 1990 ... noxious tactile stimulus
(VWT) were determined using an automated electronic von Frey apparatus (IITC ...
Taurine replacement attenuates hyperalgesia and abnormal calcium signaling in sensory neurons of STZ-D rats
F Li, IG Obrosova, O Abatan, D Tian… - American Journal of …, 2005 - Am Physiological Soc
... Digital sensory NCV (SNCV) was recorded in the digital nerve to the second toe by stimulating
with a square ... by quantifying the withdrawal threshold of the hindpaw in response to mechanical
stimulation using a von Frey anesthesiometer (model 2290C; IITC Life Science ...
Activation of presynaptic NMDA receptors coupled to NaV1. 8-resistant sodium channel C-fibers causes retrograde mechanical nociceptor sensitization
CA Parada, GG Vivancos, CH Tambeli… - Proceedings of the …, 2003 - National Acad Sciences
... Intrathecal administration of prostaglandin E 2 (PGE 2 ), glutamate, and NMDA causes a bilateral
long-lasting mechanical paw hypernociception ... reflex with a hand-held force transducer adapted
with a 0.5-mm 2 polypropylene tip (electronic von Frey hair; IITC Life Science ...
The use of an electronic von Frey device for evaluation of sensory threshold in neurologically normal dogs and those with acute spinal cord injury
SA Moore, BF Hettlich, A Waln - The Veterinary Journal, 2013 - Elsevier
... Accepted 3 November 2012 Available online 13 December 2012. Abstract. The ...
examination. von Frey device. The electronic von Frey device (IITC Life Science)
consisted of a load cell, handle, recording device and tip (Fig. 1 ...
Reproducibility of electronic von frey and von frey monofilaments testing
B Tena, B Escobar, MJ Arguis, C Cantero… - The Clinical journal …, 2012 -
... Reprints: Beatriz Tena, MD, Hospital Clinic, c/Villarroel 170, 08036 Barcelona, Spain (e-mail:
btena@clinic.ub.es ... Pain threshold was subsequently determined using a pressure algometer,
the Electronic von Frey (Electronic Von Frey Anesthesiometer IITC). ...
TrkA and PKC-epsilon in thermal burn–induced mechanical hyperalgesia in the rat
GJ Summer, KA Puntillo, C Miaskowski, OA Dina… - The Journal of …, 2006 - Elsevier
... Received 5 December 2005 Revised 12 April 2006 Accepted 12 April 2006 Available online
6 December ... threshold in animals that underwent a plantar surface burn was assessed using an
electronic von Frey (EvF) model 1601CE anesthesiometer (IITC Life Science ...
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