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暑期優(yōu)惠*！G蛋白歐聯(lián)受體42抗體等各種科研實驗抗體南京森貝伽公司*專業(yè)供應(yīng)公司抗體質(zhì)量可靠，每一個抗體都經(jīng)過嚴(yán)格檢測和穩(wěn)定性測試，保證了實驗結(jié)果的準(zhǔn)確性、敏感性、特異性。公司擁有國內(nèi)的抗體服務(wù)技術(shù)、*的儀器設(shè)備和專業(yè)的技術(shù)人員，為您提供*的售前售后服務(wù)。森貝伽始終秉承產(chǎn)品“質(zhì)量高、價格優(yōu)、信譽(yù)好”為一體，不斷努力為顧客提供更好更滿意的產(chǎn)品，咨詢訂購G蛋白歐聯(lián)受體42抗體！
英文名稱 FFAR3/GPR42
中文名稱 G蛋白歐聯(lián)受體42抗體
別    名 FFA3R; Ffar3; FFAR3_HUMAN; Free fatty acid receptor 3; G protein coupled receptor 41; G-protein coupled receptor 41; gpcr41; GPR41; gpr42.
G蛋白歐聯(lián)受體42抗體
說明書 0.2ml
研究領(lǐng)域細(xì)胞生物  免疫學(xué)  結(jié)合蛋白  G蛋白偶聯(lián)受體  細(xì)胞骨架  G蛋白信號
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分子量 39kDa
細(xì)胞定位細(xì)胞膜
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免疫原 KLH conjugated synthetic peptide derived from human FFAR3
亞    型 IgG
純化方法 affinity purified by Protein A
儲存液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
G蛋白歐聯(lián)受體42抗體
產(chǎn)品介紹 background:
G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. GPRs translate extracellular signals into intracellular signals (a process called G-protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR41 (G-protein coupled receptor 41), also known as FFAR3 (Free fatty acid receptor 3), is a 346 amino acid multi-pass membrane protein that belongs to the G protein-coupled receptor family. Expressed at high levels in adipose tissue and at lower levels throughout the body, GPR41 functions as a receptor for short chain fatty acids via elevation of intracellular calcium levels and inhibition of adenylyl cyclase.

Function:
Receptor for short chain fatty acids. The activity of this receptor is coupled to the formation of inositol 1,4,5-trisphosphate, intracellular Ca2+ mobilization, the activation of ERK 1/2 and inhibition of intracellular cAMP accumulation. Coupled exclusively to the pertussis toxin-sensitive G(i/o)-alpha protein. The rank order of potency for agonists of this receptor is propionate = pentanoate = butyrate > acetate > formate.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Highest level in adipose tissue, and lower expression across all tissues tested.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links: